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BCl-2 Inhibitor GX15-070

Full Name
BCl-2 Inhibitor GX15-070 (RE1035)
Background
A small molecular pan-Bcl-2 antagonist that can effectively interfere with the direct interaction between Mcl-1 and Bak on intact mitochondrial membranes.
Research Area Other/Reagents
Catalog Number RE1035
Alternate Name (Z)-2-(2-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole methanesulfonate
Molecular Weight 317.38
Molecular Formula C₂₀H₁₉N₃O
Appearance Off-white solid
InChi InChI=1S/C20H19N3O.CH4O3S/c1-12-8-13(2)21-16(12)10-19-20(24-3)11-18(23-19)17-9-14-6-4-5-7-15(14)22-17;1-5(2,3)4/h4-11,21,23H,1-3H3;1H3,(H,2,3,4)/b18-17-,19-10-;
Purity ≥98%
Solubility DMSO (>80 mg/ml)
Handling Protect from air and light
Storage Instruction Store at -20°C
Usage Statement Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses.
For Research Use Only. Not For Clinical Use Or Individual Users.

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