Nicotinamide adenine dinucleotide (NAD+), also known as coenzyme I, is an essential coenzyme in the redox process. In redox reactions, NADH acts as the donor of hydrogen and electrons, and NAD+, as the acceptor of hydrogen and electrons, participates in physiological processes such as respiration, photosynthesis, cellular metabolism, and energy synthesis. As coenzymes of many redox reactions in organisms, they participate in life activities and transform each other.
Figure 1. An overview of NAD metabolism. (Chong K. S., et al., 2020)
Creative Biogene has established a NAD metabolism-related small molecule detection platform based on GC/MS and ACQUITY UPLC/TripleQuad5500 (Waters/AB Sciex) to analyze NAD metabolism-related small molecules qualitatively and quantitatively. 95% of the substances involved are quantified using isotope standard.
NAD metabolism-related small molecules mainly include an oxidized NAD+, reduced form of NADH, oxidized NADP+, reduced form of NADPH, NMN, NAM, NaR, and ATP. Please contact us if your substance is not listed here. We are committed to providing professional and accurate testing and analysis services for all customers.
At the end of the experiment, Creative Biogene technicians will provide you with a detailed technical report as soon as possible, including experimental steps, relevant MS parameters, quantitative or quantitative information of the identified substances, MS images, and detailed real raw data.
Creative Biogene always provides you with customized services for mitochondrial research, and our one-stop research and analysis platform can meet all your research needs.
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