Data Independent Acquisition (DIA) is a new, holographic independent data acquisition and quantitative technique based on the trajectory of the electrostatic field. The scanning range is divided into a series of intervals with an interval of 25 Dalt, and all the peptide parent ions in the scanning interval can be scanned at ultra-high speed and secondary fragmentation, obtaining the complete peptide information. Compared with the traditional proteomics using Data Dependent Acquisition (DDA) strategy, DIA technology avoids the bias of DDA strategy for high-abundance peptide collection and fragmentation, and DIA technology has a significant advantage for the quantification of low-abundance peptides. SWATH provided by Creative Biogene is a special variant of DIA.
Figure 1. DIA technical schematic diagram. ( From LCGC North America)
Creative Biogene provides cutting-edge DIA testing and analysis services for customers around the world, easily testing hundreds of samples with a high-resolution mass spectrometer, using professional analysis software to generate a spectrum database of DIA data, quality control, and analysis, and providing high accuracy results. You just need to tell us your experimental purpose and send us your cells, and we will be responsible for all the follow-up matters of the project.
Creative Biogene has the most professional team to serve customers around the world. If you have any questions about the content of this service, please feel free to contact us. We look forward to your contact.