Cancer cells have a different metabolism than normal cells, which allows them to survive longer and grow faster. Resistance to apoptosis is a key feature of cancer cells, and given the importance of mitochondria in apoptosis, it is crucial to study the behavior of mitochondria in tumors.
Indeed, the relationship between cancer development and mitochondrial dysfunction is manifested in various ways:
In addition, nuclear gene mutations in conjunction with the following transcription factors and signaling pathways affecting mitochondrial function are also important in the development and metastasis of cancer.
Therefore, mitochondria could be a potential target for cancer therapy.
Figure 1. Mitochondria-targeted Cancer Therapies (Klein, 2020).
Creative Biogene works with you to validate and explore the pathogenesis of mitochondria-associated cancers and possible interventions, with professional services and products to support your research.
You could also benefit from our established cancer models. Creative Biogene offers comprehensive mitochondria-focused tests and services with the advantage of our cell-based and animal-based models.
In vivo/in vitro assessment of mitochondrial function can be a useful tool for mechanistic studies of cancers, as well as for the evaluation of (novel) therapeutic interventions.
Creative Biogene provides rapid mitochondrial function testing services, allowing clients to accurately analyze the relationship between disease and mitochondria.
Oxygen Consumption Rate (OCR) Measurement
Fluorescent Reporters of Mitochondrial pH
Mitochondrial Membrane Potential (MMP)
Fission and Fusion
If you have any special needs or questions regarding our services, please feel free to contact us. Creative Biogene looks forward to cooperating with you in the future.
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