Mitochondrial Glucose Metabolism

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Sugar is an organic compound whose chemical essence is polyaldehydes or polyhydroxy ketones and their derivatives. Sugar metabolism refers to a series of complex chemical reactions of glucose and glycogen in the body. The main source of sugar in the body is from food, which is digested by the human body and absorbed into monosaccharides, then transported to various tissues and cells through blood for synthesis and catabolism. The main metabolic pathways of glucose in the body are anaerobic glycolysis of glucose, aerobic oxidation, pentose phosphate pathway, uronic acid pathway, polyol pathway, glycogen synthesis, and glycogen decomposition, gluconeogenesis, and another hexose metabolism.

Figure 1. Mitochondrial and two extra-mitochondrial pathways of glucose metabolism. (William T., et al., 2009)

Creative Biogene combines GC/MS and ACQUITY UPLC/TripleQuad5500 to analyze a variety of sugars and metabolism-related sugars. of which 95% of the substances involved are quantified using standards and isotope standards.

General Strategy

Besides, Creative Biogene also provides other physical and chemical tests, including starch content determination, amylose content determination, crude polysaccharide detection, reducing sugar detection, cellulose content determination, hemicellulose content determination, lignin content determination, chitin content determination, etc. Our platform can also provide a series of services for biochemical determination of glucose metabolism.

Creative Biogene always provides you with customized services for mitochondrial research, and our one-stop research and analysis platform can meet all your research needs.

Our Advantages

• Rich experience in the detection of mitochondrial glucose metabolism
• Outstanding research team
• Unique integrated service for mitochondrial research
• Reliable data and results
• Rapid turnaround and cost-effective

Creative Biogene has the most professional team to serve customers around the world. If you have any questions about the content of this service, please feel free to contact us. We look forward to your contact.

References

1. William T., et al. " Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression. " Journal of the Neurological Sciences, 2009, 275(1-2): 106-112.
2. Li J., et al. "Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumour cell survival during energy stress." Oncogene, 2017, 36(34): 4901.

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