Mitochondrial dysfunction causes changes in a variety of biochemical indicators in the body. It is important to understand the body's acid-base system, kidney and liver function, and nutritional parameters.
Figure 1. Metabolic Panel for Mitochondria.
Metabolite analysis in blood and urine is generally the first to be performed in the initial review of mitochondria-related disease symptoms. These results often provide important insights into metabolic changes caused by mitochondrial dysfunction. Therefore, metabolic tests including sodium (Na), potassium (K), chloride (Cl), carbon dioxide (CO2), creatinine (Cr), urea nitrogen (BUN), glucose, total protein (TP), albumin (Alb), liver function (AST, ALT, bilirubin), and creatine kinase (CK) will be requested.
The anion gap will be calculated. Metabolic acidosis may occur and the anion gap may be increased. Liver dysfunction may be present.
Creative Biogene provides an accurate Metabolic Panel assay service to precisely evaluate the metabolism changes induced by mitochondria dysfunction.
Creative Biogene works with you to validate and explore the pathogenesis of mitochondria-associated diseases and possible interventions, with professional Biofluid Biochemistry assay services to support your research.
|Biofluid Biochemistry||Metabolic Panel|
|Lactate and Pyruvate Levels|
|Plasma Amino Acid Profile|
|Urine Organic Acid Profile|
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