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Brusatol

Full Name
Brusatol (RE1027)
Background
Brusatol is a kind of compound isolated from plants, which has been proved to inhibit Nrf2 signal transduction, reduce tumor burden, and improve chemotherapy resistance.
Research Area Other/Reagents
Catalog Number RE1027
Alternate Name (+)-Brusatol; (11β,12α,15β)-13,20-Epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-picras-3-en-21-oic acid methyl ester; NSC 172924; Yatansin
Molecular Weight 520.53
Molecular Formula C₂₆H₃₂O₁₁
Appearance Crystalline solid
InChi InChI=1S/C26H32O11/c1-10(2)6-15(28)37-18-20-25-9-35-26(20,23(33)34-5)21(31)17(30)19(25)24(4)8-13(27)16(29)11(3)_x000D_ 12(24)7-14(25)36-22(18)32/h6,12,14,17-21,29-31H,7-9H2,1-5H3/t12-,14+,17+,18+,19+,20+,21-,24-,25+,26-/m0/s1
MDL Number MFCD23726642
Purity ≥95% by HPLC
Solubility ~5 mg/ml in DMSO
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Instruction Store at -20ºC
Usage Statement Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses.
For Research Use Only. Not For Clinical Use Or Individual Users.
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