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GDC-0917

Full Name
GDC-0917 (RE1043)
Background
GDC-0917 is a second mitochondrial activator of caspases (Smac) mimetic, a small molecule inhibitor.
Research Area Other/Reagents
Catalog Number RE1043
Alternate Name (S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N-(2-(oxazol-2-yl)-4-phenylthiazol-5-yl)pyrrolidine-2-carboxamide; CUDC-427
Molecular Weight 564.7
Molecular Formula C₂₉H₃₆N₆O₄S
Appearance Crystalline solid
InChi InChI=1S/C29H36N6O4S/c1-18(30-2)24(36)32-23(20-12-7-4-8-13-20)29(38)35-16-9-14-21(35)25(37)34-27-22(19-10-5-3-6-11-19)33-28(40-27)26-31-15-17-39-26/h3,5-6,10-11,15,17-18,20-21,23,30H,4,7-9,12-14,16H2,1-2H3,(H,32,36)(H,34,37)/t18-,21?,23-/m0/s1
Purity ≥98% by HPLC
Solubility DMSO
Handling Protect from air and light
Storage Instruction Store at -20°C
Usage Statement Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses.
For Research Use Only. Not For Clinical Use Or Individual Users.

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