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mtCheck™ Phosphoenolpyruvate Carboxykinase 1 Inhibitor Screening Kit

Full Name
mtCheck™ Phosphoenolpyruvate Carboxykinase 1 Inhibitor Screening Kit (KITA1036)
Product Name mtCheck™ Phosphoenolpyruvate Carboxykinase 1 Inhibitor Screening Kit (KITA1036)
Description This kit provides a high-throughput, fast Screening/characterizing/studying potential inhibitors of Human PEPCK1 method.Phosphoenolpyruvate Carboxykinase (PEPCK, EC 4.1.1.32) is an enzyme that belongs to the family of lytic enzymes. With the presence of GTP, it catalyzes the reversible conversion of oxaloacetate to phosphoenolpyruvate, GDP and CO2. PEPCK1 is the rate-controlling step of gluconeogenesis and the key gluconeogenic enzyme in the liver and kidney.Overexpression of PEPCK1 in the liver leads to excessive glucose production and a type II diabetic phenotype in mice. Characterization of PEPCK1 inhibitors is a practical strategy for the treatment of type II diabetes and obesity.
Catalog Number KITA1036
Species Reactivity Mammals
Storage Instruction Store at -20°C
Usage Statement Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses.
Detection Method Absorbance (570 nm)
For Research Use Only. Not For Clinical Use Or Individual Users.

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