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Rottlerin

Full Name
Rottlerin (RE1055)
Background
Rottlerin can uncouple mitochondria and affect the production of reactive oxygen species in mitochondria. It can also induce autophagy by inhibiting mTORC1.
Research Area Other/Reagents
Catalog Number RE1055
Alternate Name 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone; Mallotoxin
Molecular Weight 516.55
Molecular Formula C₃₀H₂₈O₈
Appearance Orange to brown solid
InChi InChI=1S/C30H28O8/c1-15-24(33)19(27(36)22(16(2)31)25(15)34)14-20-26(35)18-12-13-30(3,4)38-29(18)23(28(20)37)21(32)11-10-17-8-6-5-7-9-17/h5-13,33-37H,14H2,1-4H3/b11-10+
MDL Number MFCD00017361
Purity ≥98% by HPLC
Solubility DMSO (30 mg/ml) or Ethanol (1 mg/ml)
Handling Protect from air and light
Storage Instruction Store at -20°C
Usage Statement Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses.
For Research Use Only. Not For Clinical Use Or Individual Users.
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